| Net income | |
| Depreciation and amortization | 63.1M |
| Amortization of Credit Agreement deferred financing costs | |
| Accretion of interest income on short-term investments | |
| Deferred income taxes | |
| Provision for uncertain tax positions | |
| Tax benefit related to the exercise of employee stock options | -507K |
| Deferred revenue | |
| Deferred product manufacturing costs | |
| Recognition of deferred revenue | |
| Amortization of deferred product manufacturing costs | |
| Accrued profit sharing and royalty expense | |
| Payments of profit sharing and royalty expense | |
| Payments of accrued litigation settlements | |
| Share-based compensation expense | 23.38M |
| Bad debt expense | 48.04M |
| Accounts receivable | 36.82M |
| Inventory | -50.52M |
| Prepaid expenses and other assets | -42.66M |
| Accounts payable, accrued expenses and income taxes payable | |
| Other liabilities | 2.28M |
| Net cash (used in) provided by operating activities | 97.77M |
| Purchase of short-term investments | |
| Maturities of short-term investments | 0 |
| Purchases of property, plant and equipment | -31.86M |
| Net cash provided by (used in) investing activities | -604.81M |
| Tax benefit related to the exercise of employee stock options | 507K |
| Proceeds from exercise of stock options and ESPP | |
| Net cash provided by financing activities | 397.78M |
| Net increase in cash and cash equivalents | -108.23M |
| Cash and cash equivalents, beginning of period | 340.35M |
| Cash and cash equivalents, end of period | 232.12M |
| Cash paid for interest | 8.21M |
| Cash paid for income taxes | |