ACUMEN Pharmaceuticals nominates two Alzheimer's drug candidates

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Acumen Pharmaceuticals Announces Nomination of Two Enhanced Brain Delivery™ (EBD™) Development Candidates for the Treatment of Alzheimer’s Disease

June 16, 2026 7:30 AM EDT

ACU301 and ACU401 were nominated in the EBD program as part of the exercise of Acumens option under its license agreement with JCR PharmaceuticalsEBD technology represents the only anti-amyloid oligomer program combining a validated blood-brain barrier-penetrating technology with a therapeutic antibody tested in the clinicAcumens EBD candidates are designed to achieve higher brain penetration with potential for improved safety compared to native antibodies and delivered in a stable, low volume subcutaneous administration formatInvestigational New Drug (IND)-enabling activities are... More