Neurocrine shows sustained pediatric results for CRENESSITY in two-year study

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Neurocrine Biosciences Presents New Two-Year CRENESSITY® (crinecerfont) Data Demonstrating Durable Hormone Control, Reduced Glucocorticoid Exposure and Meaningful Clinical Improvements in Pediatric P

May 1, 2026 4:05 PM EDT

At two years, 60% of patients who were overweight or obese at baseline experienced clinically meaningful improvements in body mass index, and 61% of those with insulin resistance at baseline were no longer insulin resistantImproved outcomes associated with excess androgens, including acne and androstenedione-to-testosterone ratio were also observedCRENESSITY delivered sustained reductions in adrenocorticotropic hormone and 17-hydroxyprogesterone, while enabling lower, more physiologic glucocorticoid dosing

SAN DIEGO, May 1, 2026 /PRNewswire/... More