Relay announces plans for Phase 3 breast cancer trial of drug combination
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Relay Therapeutics Announces Clinical Data for Zovegalisib plus Atirmociclib Triplet Combination Supportive of Further Development in Frontline Metastatic Breast Cancer
April 27, 2026 6:00 AM EDTZovegalisib + atirmociclib + AI selected as triplet regimen for frontline development
Compelling efficacy and tolerability data for zovegalisib triplet in median 3L patients
44% ORR in heavily pre-treated, CDK4/6-experienced patients (median third-line); ORR is similar across kinase and non-kinase PIK3CA mutations
Phase 3 frontline trial in endocrine sensitive patients expected to initiate in early 2027, subject to regulatory feedback
Supply agreement in place with Pfizer to supply atirmociclib for the Phase 3 frontline trial
Relay Therapeutics to host a conference call... More
