SenesTech posts mixed Q1 results amid e-commerce transition

SenesTech Inc. (NASDAQ: SNES) reported first-quarter revenue of $493,000, a 2% increase from $485,000 in the same period last year, according to financial results released by the company.

The rodent birth control product manufacturer appointed Michael Edell as chief executive officer in May 2026. Direct-to-consumer revenue increased 42% to $194,000 in the first quarter, while subscription revenue rose 44% to $56,000 compared to the prior year period.

The company transitioned from third-party management to in-house management of its Amazon sales operations during the quarter. Third-party e-commerce revenues declined to $17,000 from $157,000 in the first quarter of 2025 due to this transition.

Business-to-business revenue increased 57% to $298,000 in the first quarter. Gross margin expanded to 68.6%, which the company described as a record level.

Net loss for the quarter was $2.1 million, compared to $1.7 million in the first quarter of 2025. The quarter included $443,000 in severance costs and one-time legal expenses. Adjusted EBITDA loss was $1.6 million versus $1.5 million in the prior year period.

Cash and cash equivalents totaled $6.8 million at the end of the quarter. The company reported that April 2026 e-commerce sales increased 163% to $146,000 compared to April 2025.

SenesTech continues municipal deployment programs in Chicago, Boston, Washington D.C., and New York City. The company's 12-month New York City rat contraception pilot program is expected to conclude this month.

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