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After-hours movers: AMD, SMCI, GOOGL, AVTX, ANET, UPST, TEM

May 5, 2026 4:59 PM EDT

After-hours movers:

The Gainers

Avalo Therapeutics (AVTX) | +60% The day's standout performer. Shares skyrocketed after the company reported successful Phase 2 trial results for its drug targeting hidradenitis suppurativa.

Super Micro Computer (SMCI) | +17% Despite some "top-line weakness" (missing revenue targets), investors cheered a significant beat on the bottom line (earnings). Most importantly, their Q4 2026 outlook is aggressive:

Projected Revenue: $11–$12.5B (Consensus: $11.3B)

Projected EPS: $0.65–$0.79 (Consensus: $0.56)

AMD (AMD) | +5% Advanced Micro Devices delivered a "beat and raise" quarter, showing strength in both current performance and future outlook.

Q1 EPS: $1.37 (Beat by $0.10)

Q1 Revenue: $10.25B (Beat by $0.4B)

Q2 Guidance: $11.2B (Consensus: $10.5B)

Alphabet (GOOGL) | +2% The tech giant gained momentum following reports that Anthropic has committed to spending roughly $200 billion with Google Cloud over the next five years.

The Decliners

Upstart Holdings (UPST) | -13% The stock fell sharply after the company merely maintained its full-year revenue guidance of $1.4 billion, failing to provide the upward revision investors were hunting for.

Arista Networks (ANET) | -11% In a classic "sell the news" event, the stock tumbled despite beating estimates. Investors labeled the Q2 revenue guidance of $2.8 billion (just slightly above the $2.78B consensus) as lackluster.

Tempus AI (TEM) | -9% With revenue and guidance simply matching analyst expectations, the lack of a "surprise" factor led to a sell-off as the market sought higher growth signals.



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