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   <title>Form  20-F       TAKEDA PHARMACEUTICAL     For: Mar 31</title>
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Filed on: June 17, 2026
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   <title>Form  20-F       TAKEDA PHARMACEUTICAL     For: Mar 31</title>
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   <title>Form  20-F       TAKEDA PHARMACEUTICAL     For: Mar 31</title>
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   <title>Takeda Pharmaceutical (4502:JP) (TAK) PT Lowered to JPY6,500 at Nomura/Instinet</title>
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   <description>Nomura/Instinet analyst Hiroyuki Matsubara lowered the price target on Takeda Pharmaceutical (4502:JP) (NYSE: TAK) to JPY6,500.00  (from JPY6,700.00) while maintaining a Buy rating.</description>
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   <title>Takeda Pharmaceutical (4502:JP) (TAK) PT Lowered to JPY6,500 at Nomura/Instinet</title>
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   <description>Nomura/Instinet analyst Hiroyuki Matsubara lowered the price target on Takeda Pharmaceutical (4502:JP) (NYSE: TAK) to JPY6,500.00  (from JPY6,700.00) while maintaining a Buy rating.</description>
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   <title>Takeda Pharmaceutical (4502:JP) (TAK) PT Lowered to JPY6,500 at Nomura/Instinet</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Takeda+Pharmaceutical+%284502%3AJP%29+%28TAK%29+PT+Lowered+to+JPY6%2C500+at+NomuraInstinet/26650361.html</link>
   <description>Nomura/Instinet analyst Hiroyuki Matsubara lowered the price target on Takeda Pharmaceutical (4502:JP) (NYSE: TAK) to JPY6,500.00  (from JPY6,700.00) while maintaining a Buy rating.</description>
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   <title>Takeda Pharmaceutical (4502:JP) (TAK) PT Lowered to JPY6,500 at Nomura/Instinet</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Takeda+Pharmaceutical+%284502%3AJP%29+%28TAK%29+PT+Lowered+to+JPY6%2C500+at+NomuraInstinet/26650361.html</link>
   <description>Nomura/Instinet analyst Hiroyuki Matsubara lowered the price target on Takeda Pharmaceutical (4502:JP) (NYSE: TAK) to JPY6,500.00  (from JPY6,700.00) while maintaining a Buy rating.</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Analyst+PT+Change/Takeda+Pharmaceutical+%284502%3AJP%29+%28TAK%29+PT+Lowered+to+JPY6%2C500+at+NomuraInstinet/26650361.html</guid>
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   <title>Goldman Sachs Reiterates Neutral Rating on Takeda Pharmaceutical (4502:JP) (TAK)</title>
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   <description>&lt;p&gt;Goldman Sachs analyst Akinori Ueda reiterated a Neutral rating and JPY5,300.00 price target on Takeda Pharmaceutical (4502:JP) (NYSE: TAK).&lt;/p&gt;</description>
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   <title>Goldman Sachs Reiterates Neutral Rating on Takeda Pharmaceutical (4502:JP) (TAK)</title>
   <link>http://www.streetinsider.com/Intl+Ratings/Goldman+Sachs+Reiterates+Neutral+Rating+on+Takeda+Pharmaceutical+%284502%3AJP%29+%28TAK%29/26649349.html</link>
   <description>&lt;p&gt;Goldman Sachs analyst Akinori Ueda reiterated a Neutral rating and JPY5,300.00 price target on Takeda Pharmaceutical (4502:JP) (NYSE: TAK).&lt;/p&gt;</description>
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   <pubDate>Tue, 16 Jun 2026 00:22:01 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
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&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
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   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
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&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
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&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
   <pubDate>Mon, 15 Jun 2026 12:00:00 -0400</pubDate>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</guid>
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   <title>New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1</title>
   <link>http://www.streetinsider.com/Business+Wire/New+Pivotal+Study+Data+Show+Takeda%E2%80%99s+Oveporexton+Improved+Daily+Function%2C+Cognition+and+Nighttime+Sleep+for+People+with+Narcolepsy+Type+1/26646093.html</link>
   <description>
&lt;p&gt;
- &lt;i&gt;Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms
&lt;br&gt;&lt;/br&gt;&lt;/i&gt;- &lt;i&gt;Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    OSAKA, Japan &amp;amp; CAMBRIDGE, Mass.--(BUSINESS WIRE)--
Takeda (&lt;a target=&quot;_blank&quot; rel=&quot;nofollow&quot; href=&quot;https://cts.businesswire.com/ct/CT?id=smartlink&amp;amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;amp;esheet=54552126&amp;amp;newsitemid=20260615651327&amp;amp;lan=en-US&amp;amp;anchor=TSE%3A4502%2FNYSE%3ATAK&amp;amp;index=1&amp;amp;md5=2735913f416631dcf87557e4849f8403&quot; shape=&quot;rect&quot;&gt;TSE:4502/NYSE:TAK&lt;/a&gt;)&lt;b&gt; &lt;/b&gt;today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1</description>
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