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   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Investing/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
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   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">NVCR</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">OKLO</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">PFE</category>
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   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Investing/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
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   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">ACN</category>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">PFE</category>
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   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Investing/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
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   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">OKLO</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">PFE</category>
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   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Investing/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Investing/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</guid>
   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
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  <item>
   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Investing/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Investing/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</guid>
   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
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  <item>
   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</guid>
   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
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  <item>
   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</guid>
   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">ACN</category>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">OKLO</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">PFE</category>
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  <item>
   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</guid>
   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">ACN</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">CAST</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">NVCR</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">OKLO</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">PFE</category>
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  <item>
   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</guid>
   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">ACN</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">CAST</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">NVCR</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">OKLO</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">PFE</category>
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  <item>
   <title>FreeCast surges premarket; Accenture, Novocure slide</title>
   <link>http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</link>
   <description>&lt;p&gt;Investing.com - U.S. stock futures ticked higher on Thursday, as the signing of an interim Middle East peace deal helped ease concerns sparked by the Federal Reserve’s hawkish policy outlook.&lt;/p&gt;
&lt;p&gt;&lt;/p&gt;
&lt;p&gt;By 0750 ET (11:50 GMT), the Dow futures contract had risen 0.12%, S&amp;amp;P 500 futures had gained 0.7%, and Nasdaq 100 futures had jumped 1.24%.&lt;/p&gt;
&lt;p&gt;Technology stocks were among the strongest performers in premarket trading, while investors also reacted to earnings-related updates, executive changes and healthcare developments.&lt;/p&gt;
&lt;p&gt;Here are some of the biggest premarket U.S. stock movers today:&lt;/p&gt;
&lt;p&gt;&lt;span itemscope=&quot;&quot; itemtype=&quot;http://schema.org/Corporation&quot;&gt;&lt;span itemprop=&quot;name&quot;&gt;Accenture&lt;/span&gt;&lt;/span&gt; plc (NYSE:ACN) tumbled more than 11% after the consulting giant trimmed the</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Special+Reports/FreeCast+surges+premarket%3B+Accenture%2C+Novocure+slide/26663150.html</guid>
   <pubDate>Thu, 18 Jun 2026 08:02:46 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">ACN</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">CAST</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">NVCR</category>
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  <item>
   <title>Novocure's TRIDENT trial misses primary endpoint in glioblastoma</title>
   <link>http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</link>
   <description>

&lt;p&gt;Novocure (NASDAQ: NVCR) announced that its Phase 3 TRIDENT trial failed to meet its primary endpoint, showing no statistically significant improvement in overall survival when Tumor Treating Fields (TTFields) therapy was initiated at the start of chemoradiation compared to initiating it during the maintenance phase of treatment for newly diagnosed glioblastoma.&lt;/p&gt;

&lt;p&gt;In the intent-to-treat population, patients who began TTFields therapy at the start of chemoradiation had a median overall survival of 17.7 months, compared to 17.5 months for those who began TTFields therapy during the maintenance phase (HR 0.953; p=0.519).&lt;/p&gt;

&lt;p&gt;The trial enrolled 981 patients who were randomized shortly after surgery. One-,</description>
   <guid isPermaLink="true">http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</guid>
   <pubDate>Thu, 18 Jun 2026 07:00:37 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">A.21855783</category>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">O.15717088</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">O.20142229</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">O.23924816</category>
   	  </item>
  <item>
   <title>Novocure's TRIDENT trial misses primary endpoint in glioblastoma</title>
   <link>http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</link>
   <description>

&lt;p&gt;Novocure (NASDAQ: NVCR) announced that its Phase 3 TRIDENT trial failed to meet its primary endpoint, showing no statistically significant improvement in overall survival when Tumor Treating Fields (TTFields) therapy was initiated at the start of chemoradiation compared to initiating it during the maintenance phase of treatment for newly diagnosed glioblastoma.&lt;/p&gt;

&lt;p&gt;In the intent-to-treat population, patients who began TTFields therapy at the start of chemoradiation had a median overall survival of 17.7 months, compared to 17.5 months for those who began TTFields therapy during the maintenance phase (HR 0.953; p=0.519).&lt;/p&gt;

&lt;p&gt;The trial enrolled 981 patients who were randomized shortly after surgery. One-,</description>
   <guid isPermaLink="true">http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</guid>
   <pubDate>Thu, 18 Jun 2026 07:00:37 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">A.21855783</category>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">NVCR</category>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">O.23924816</category>
   	  </item>
  <item>
   <title>Novocure's TRIDENT trial misses primary endpoint in glioblastoma</title>
   <link>http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</link>
   <description>

&lt;p&gt;Novocure (NASDAQ: NVCR) announced that its Phase 3 TRIDENT trial failed to meet its primary endpoint, showing no statistically significant improvement in overall survival when Tumor Treating Fields (TTFields) therapy was initiated at the start of chemoradiation compared to initiating it during the maintenance phase of treatment for newly diagnosed glioblastoma.&lt;/p&gt;

&lt;p&gt;In the intent-to-treat population, patients who began TTFields therapy at the start of chemoradiation had a median overall survival of 17.7 months, compared to 17.5 months for those who began TTFields therapy during the maintenance phase (HR 0.953; p=0.519).&lt;/p&gt;

&lt;p&gt;The trial enrolled 981 patients who were randomized shortly after surgery. One-,</description>
   <guid isPermaLink="true">http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</guid>
   <pubDate>Thu, 18 Jun 2026 07:00:37 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">A.21855783</category>
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   <title>Novocure's TRIDENT trial misses primary endpoint in glioblastoma</title>
   <link>http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</link>
   <description>

&lt;p&gt;Novocure (NASDAQ: NVCR) announced that its Phase 3 TRIDENT trial failed to meet its primary endpoint, showing no statistically significant improvement in overall survival when Tumor Treating Fields (TTFields) therapy was initiated at the start of chemoradiation compared to initiating it during the maintenance phase of treatment for newly diagnosed glioblastoma.&lt;/p&gt;

&lt;p&gt;In the intent-to-treat population, patients who began TTFields therapy at the start of chemoradiation had a median overall survival of 17.7 months, compared to 17.5 months for those who began TTFields therapy during the maintenance phase (HR 0.953; p=0.519).&lt;/p&gt;

&lt;p&gt;The trial enrolled 981 patients who were randomized shortly after surgery. One-,</description>
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   <title>Novocure's TRIDENT trial misses primary endpoint in glioblastoma</title>
   <link>http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</link>
   <description>

&lt;p&gt;Novocure (NASDAQ: NVCR) announced that its Phase 3 TRIDENT trial failed to meet its primary endpoint, showing no statistically significant improvement in overall survival when Tumor Treating Fields (TTFields) therapy was initiated at the start of chemoradiation compared to initiating it during the maintenance phase of treatment for newly diagnosed glioblastoma.&lt;/p&gt;

&lt;p&gt;In the intent-to-treat population, patients who began TTFields therapy at the start of chemoradiation had a median overall survival of 17.7 months, compared to 17.5 months for those who began TTFields therapy during the maintenance phase (HR 0.953; p=0.519).&lt;/p&gt;

&lt;p&gt;The trial enrolled 981 patients who were randomized shortly after surgery. One-,</description>
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   <pubDate>Thu, 18 Jun 2026 07:00:37 -0400</pubDate>
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   <title>Novocure's TRIDENT trial misses primary endpoint in glioblastoma</title>
   <link>http://www.streetinsider.com/FDA/Novocure%27s+TRIDENT+trial+misses+primary+endpoint+in+glioblastoma/26662660.html</link>
   <description>

&lt;p&gt;Novocure (NASDAQ: NVCR) announced that its Phase 3 TRIDENT trial failed to meet its primary endpoint, showing no statistically significant improvement in overall survival when Tumor Treating Fields (TTFields) therapy was initiated at the start of chemoradiation compared to initiating it during the maintenance phase of treatment for newly diagnosed glioblastoma.&lt;/p&gt;

&lt;p&gt;In the intent-to-treat population, patients who began TTFields therapy at the start of chemoradiation had a median overall survival of 17.7 months, compared to 17.5 months for those who began TTFields therapy during the maintenance phase (HR 0.953; p=0.519).&lt;/p&gt;

&lt;p&gt;The trial enrolled 981 patients who were randomized shortly after surgery. One-,</description>
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   <pubDate>Thu, 18 Jun 2026 07:00:37 -0400</pubDate>
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   <title>Novocure Announces Topline Data from the Phase 3 TRIDENT Trial Evaluating Earlier Use of Tumor Treating Fields Therapy in Newly Diagnosed Glioblastoma</title>
   <link>http://www.streetinsider.com/Press+Releases/Novocure+Announces+Topline+Data+from+the+Phase+3+TRIDENT+Trial+Evaluating+Earlier+Use+of+Tumor+Treating+Fields+Therapy+in+Newly+Diagnosed+Glioblastoma/26662632.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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   <title>Novocure Announces Topline Data from the Phase 3 TRIDENT Trial Evaluating Earlier Use of Tumor Treating Fields Therapy in Newly Diagnosed Glioblastoma</title>
   <link>http://www.streetinsider.com/Press+Releases/Novocure+Announces+Topline+Data+from+the+Phase+3+TRIDENT+Trial+Evaluating+Earlier+Use+of+Tumor+Treating+Fields+Therapy+in+Newly+Diagnosed+Glioblastoma/26662632.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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   <title>Novocure Announces Topline Data from the Phase 3 TRIDENT Trial Evaluating Earlier Use of Tumor Treating Fields Therapy in Newly Diagnosed Glioblastoma</title>
   <link>http://www.streetinsider.com/Press+Releases/Novocure+Announces+Topline+Data+from+the+Phase+3+TRIDENT+Trial+Evaluating+Earlier+Use+of+Tumor+Treating+Fields+Therapy+in+Newly+Diagnosed+Glioblastoma/26662632.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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   <title>Novocure Announces Topline Data from the Phase 3 TRIDENT Trial Evaluating Earlier Use of Tumor Treating Fields Therapy in Newly Diagnosed Glioblastoma</title>
   <link>http://www.streetinsider.com/Press+Releases/Novocure+Announces+Topline+Data+from+the+Phase+3+TRIDENT+Trial+Evaluating+Earlier+Use+of+Tumor+Treating+Fields+Therapy+in+Newly+Diagnosed+Glioblastoma/26662632.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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   <title>Novocure Announces Topline Data from the Phase 3 TRIDENT Trial Evaluating Earlier Use of Tumor Treating Fields Therapy in Newly Diagnosed Glioblastoma</title>
   <link>http://www.streetinsider.com/Press+Releases/Novocure+Announces+Topline+Data+from+the+Phase+3+TRIDENT+Trial+Evaluating+Earlier+Use+of+Tumor+Treating+Fields+Therapy+in+Newly+Diagnosed+Glioblastoma/26662632.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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   <title>Novocure Announces Topline Data from the Phase 3 TRIDENT Trial Evaluating Earlier Use of Tumor Treating Fields Therapy in Newly Diagnosed Glioblastoma</title>
   <link>http://www.streetinsider.com/Press+Releases/Novocure+Announces+Topline+Data+from+the+Phase+3+TRIDENT+Trial+Evaluating+Earlier+Use+of+Tumor+Treating+Fields+Therapy+in+Newly+Diagnosed+Glioblastoma/26662632.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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   <title>Novocure Announces Topline Data from the Phase 3 TRIDENT Trial Evaluating Earlier Use of Tumor Treating Fields Therapy in Newly Diagnosed Glioblastoma</title>
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   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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The Phase 3 TRIDENT trial enrolled patients with glioblastoma prior to the initiation of chemoradiation and evaluated the benefit of initiating Tumor Treating Fields (TTFields) therapy at the start of chemoradiation compared to initiating TTFields therapy in the maintenance phase

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
TRIDENT did not meet its primary endpoint of demonstrating a statistically significant increase in overall survival for patients in the intent-to-treat (ITT) population who initiated TTFields therapy at the start of chemoradiation

&lt;/p&gt;&lt;p class=&quot;bwalignc&quot;&gt;
Results from TRIDENT demonstrated a durable survival benefit for patients in both arms of the trial, no new safety signals were observed, and early initiation of TTFields</description>
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