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   <title>Form  4          Mineralys Therapeutics,   For: Jun 17  Filed by: Karydas Daphne</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Mineralys+Therapeutics%2C+++For%3A+Jun+17++Filed+by%3A+Karydas+Daphne/26661629.html</link>
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   <pubDate>Wed, 17 Jun 2026 21:18:00 -0400</pubDate>
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   <title>Form  4          Mineralys Therapeutics,   For: Jun 17  Filed by: Karydas Daphne</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Mineralys+Therapeutics%2C+++For%3A+Jun+17++Filed+by%3A+Karydas+Daphne/26661629.html</link>
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   <pubDate>Wed, 17 Jun 2026 21:18:00 -0400</pubDate>
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   <title>Form  4          Mineralys Therapeutics,   For: Jun 15  Filed by: Rodman David Malcom</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Mineralys+Therapeutics%2C+++For%3A+Jun+15++Filed+by%3A+Rodman+David+Malcom/26661630.html</link>
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   <title>Form  4          Mineralys Therapeutics,   For: Jun 15  Filed by: Rodman David Malcom</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Mineralys+Therapeutics%2C+++For%3A+Jun+15++Filed+by%3A+Rodman+David+Malcom/26661630.html</link>
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   <title>Form  144        Mineralys Therapeutics,                Filed by: Rodman David Malcom</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++144++++++++Mineralys+Therapeutics%2C++++++++++++++++Filed+by%3A+Rodman+David+Malcom/26660199.html</link>
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   <title>Form  144        Mineralys Therapeutics,                Filed by: Rodman David Malcom</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++144++++++++Mineralys+Therapeutics%2C++++++++++++++++Filed+by%3A+Rodman+David+Malcom/26660199.html</link>
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   <pubDate>Wed, 17 Jun 2026 16:20:00 -0400</pubDate>
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   <title>Form  144        Mineralys Therapeutics,                Filed by: Karydas Daphne</title>
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   <title>Form  144        Mineralys Therapeutics,                Filed by: Karydas Daphne</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++144++++++++Mineralys+Therapeutics%2C++++++++++++++++Filed+by%3A+Karydas+Daphne/26660128.html</link>
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   <title>Form  144        Mineralys Therapeutics,                Filed by: Rodman David Malcom</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++144++++++++Mineralys+Therapeutics%2C++++++++++++++++Filed+by%3A+Rodman+David+Malcom/26648288.html</link>
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   <pubDate>Mon, 15 Jun 2026 16:58:00 -0400</pubDate>
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   <title>Form  144        Mineralys Therapeutics,                Filed by: Rodman David Malcom</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++144++++++++Mineralys+Therapeutics%2C++++++++++++++++Filed+by%3A+Rodman+David+Malcom/26648288.html</link>
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   <title>Mineralys presents heart failure biomarker data for lorundrostat at ENDO 2026</title>
   <link>http://www.streetinsider.com/Corporate+News/Mineralys+presents+heart+failure+biomarker+data+for+lorundrostat+at+ENDO+2026/26642925.html</link>
   <description>&lt;p&gt;Mineralys Therapeutics Inc (NASDAQ: MLYS) presented data showing its investigational drug lorundrostat was associated with reductions in heart failure risk biomarkers in patients with uncontrolled hypertension.&lt;/p&gt;&lt;p&gt;The company presented the findings in a late-breaking poster at the Endocrine Society's annual meeting ENDO 2026 in Chicago. The analysis examined circulating protein biomarkers from 1,004 participants in the company's Launch-HTN and Advance-HTN trials after 12 weeks of treatment.&lt;/p&gt;&lt;p&gt;According to the data, lorundrostat showed significant reductions in 6 of 11 candidate causal risk biomarkers of incident heart failure, including NT-proBNP. The treatment also led to coordinated changes in key biomarkers, with reductions in markers</description>
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   <pubDate>Sun, 14 Jun 2026 14:01:03 -0400</pubDate>
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   <title>Mineralys presents heart failure biomarker data for lorundrostat at ENDO 2026</title>
   <link>http://www.streetinsider.com/FDA/Mineralys+presents+heart+failure+biomarker+data+for+lorundrostat+at+ENDO+2026/26642925.html</link>
   <description>&lt;p&gt;Mineralys Therapeutics Inc (NASDAQ: MLYS) presented data showing its investigational drug lorundrostat was associated with reductions in heart failure risk biomarkers in patients with uncontrolled hypertension.&lt;/p&gt;&lt;p&gt;The company presented the findings in a late-breaking poster at the Endocrine Society's annual meeting ENDO 2026 in Chicago. The analysis examined circulating protein biomarkers from 1,004 participants in the company's Launch-HTN and Advance-HTN trials after 12 weeks of treatment.&lt;/p&gt;&lt;p&gt;According to the data, lorundrostat showed significant reductions in 6 of 11 candidate causal risk biomarkers of incident heart failure, including NT-proBNP. The treatment also led to coordinated changes in key biomarkers, with reductions in markers</description>
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   <title>Mineralys Therapeutics Presents Late-Breaking Data on Lorundrostat and Heart Failure Risk Biomarkers at The Endocrine Society Annual Meeting (ENDO 2026)</title>
   <link>http://www.streetinsider.com/Press+Releases/Mineralys+Therapeutics+Presents+Late-Breaking+Data+on+Lorundrostat+and+Heart+Failure+Risk+Biomarkers+at+The+Endocrine+Society+Annual+Meeting+%28ENDO+2026%29/26642909.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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   <title>Mineralys Therapeutics Presents Late-Breaking Data on Lorundrostat and Heart Failure Risk Biomarkers at The Endocrine Society Annual Meeting (ENDO 2026)</title>
   <link>http://www.streetinsider.com/Press+Releases/Mineralys+Therapeutics+Presents+Late-Breaking+Data+on+Lorundrostat+and+Heart+Failure+Risk+Biomarkers+at+The+Endocrine+Society+Annual+Meeting+%28ENDO+2026%29/26642909.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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   <title>Mineralys Therapeutics Presents Late-Breaking Data on Lorundrostat and Heart Failure Risk Biomarkers at The Endocrine Society Annual Meeting (ENDO 2026)</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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   <title>Mineralys Therapeutics Presents Late-Breaking Data on Lorundrostat and Heart Failure Risk Biomarkers at The Endocrine Society Annual Meeting (ENDO 2026)</title>
   <link>http://www.streetinsider.com/Press+Releases/Mineralys+Therapeutics+Presents+Late-Breaking+Data+on+Lorundrostat+and+Heart+Failure+Risk+Biomarkers+at+The+Endocrine+Society+Annual+Meeting+%28ENDO+2026%29/26642909.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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   <title>Mineralys Therapeutics Presents Late-Breaking Data on Lorundrostat and Heart Failure Risk Biomarkers at The Endocrine Society Annual Meeting (ENDO 2026)</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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   <title>Mineralys Therapeutics Presents Late-Breaking Data on Lorundrostat and Heart Failure Risk Biomarkers at The Endocrine Society Annual Meeting (ENDO 2026)</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Lorundrostat was associated with significant reductions in heart failure risk biomarkers in a proteomic analysis of data from participants with uncontrolled hypertension –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;– Coordinated reductions in biomarkers of fibrosis and heart failure suggest lorundrostat may favorably modulate the physiological processes that drive heart failure –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;RADNOR, Pa., June  14, 2026  (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicines to target hypertension and aldosterone-related adverse outcomes in comorbid conditions such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated</description>
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