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   <title>Form  424B2      Opus Genetics, Inc.                  </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++424B2++++++Opus+Genetics%2C+Inc.++++++++++++++++++/26656829.html</link>
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   <pubDate>Wed, 17 Jun 2026 07:26:00 -0400</pubDate>
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   <title>Form  424B2      Opus Genetics, Inc.                  </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++424B2++++++Opus+Genetics%2C+Inc.++++++++++++++++++/26656829.html</link>
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   <pubDate>Wed, 17 Jun 2026 07:26:00 -0400</pubDate>
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   <title>H.C. Wainwright Reiterates Buy Rating on Opus Genetics (IRD)</title>
   <link>http://www.streetinsider.com/Analyst+Comments/H.C.+Wainwright+Reiterates+Buy+Rating+on+Opus+Genetics+%28IRD%29/26656616.html</link>
   <description>&lt;p&gt;H.C. Wainwright analyst Matthew Caufield reiterated a Buy rating and $8.00 price target on Opus Genetics (NASDAQ: IRD).&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;Opus Genetics hosted a KOL webinar and discussion highlighting the company’s inherited retinal disease (IRD) gene therapy pipeline including: (1) preclinical programs targeting RDH12, MERTK, and RHO mutations; as well as (2) ongoing development for the LCA5 and BEST1 clinical programs. We emphasize the therapeutic goal across programs is to restore vision and stop blindness progression through AAV-based one-time durable subretinal gene therapy delivery, respectively coding for the compromised protein expression otherwise driving retinal degeneration. Among these IRD programs, targeting</description>
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   <pubDate>Wed, 17 Jun 2026 06:49:45 -0400</pubDate>
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   <title>Form  EFFECT     Opus Genetics, Inc.                  </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++EFFECT+++++Opus+Genetics%2C+Inc.++++++++++++++++++/26656418.html</link>
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   <pubDate>Wed, 17 Jun 2026 06:03:00 -0400</pubDate>
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   <title>Form  EFFECT     Opus Genetics, Inc.                  </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++EFFECT+++++Opus+Genetics%2C+Inc.++++++++++++++++++/26656418.html</link>
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   <pubDate>Wed, 17 Jun 2026 06:03:00 -0400</pubDate>
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   <title>Opus Genetics (IRD) Reiterated at Market Outperform by Citizens after R&amp;D Day</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Opus+Genetics+%28IRD%29+Reiterated+at+Market+Outperform+by+Citizens+after+R%26D+Day/26656067.html</link>
   <description>&lt;p&gt;Citizens analyst Jonathan Wolleben reiterated a Market Outperform rating and $11.00 price target on Opus Genetics (NASDAQ: IRD).&lt;/p&gt;&lt;p&gt;The analyst commented, &quot;Opus’s R&amp;D Day was impressive not only for the retinal expert star power assembled, but for the clear and detailed messaging for the future growth of the company over the midto-long term. Management has assembled a pipeline of attractive gene therapy candidates and developed a clinical and regulatory strategy that should allow for accelerated paths to approval. First up is OPGx-LCA5, where new two-year data unveiled at the R&amp;D Day support a durable benefit, which we expect to last for</description>
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   <pubDate>Wed, 17 Jun 2026 04:19:57 -0400</pubDate>
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   <title>Form  8-K        Opus Genetics, Inc.       For: Jun 16</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Opus+Genetics%2C+Inc.+++++++For%3A+Jun+16/26654207.html</link>
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   <pubDate>Tue, 16 Jun 2026 16:11:00 -0400</pubDate>
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   <title>Form  8-K        Opus Genetics, Inc.       For: Jun 16</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Opus+Genetics%2C+Inc.+++++++For%3A+Jun+16/26654207.html</link>
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   <pubDate>Tue, 16 Jun 2026 16:11:00 -0400</pubDate>
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   <title>Opus Genetics outlines five gene therapy programs for retinal diseases</title>
   <link>http://www.streetinsider.com/Corporate+News/Opus+Genetics+outlines+five+gene+therapy+programs+for+retinal+diseases/26654029.html</link>
   <description>&lt;p&gt;Opus Genetics, Inc. (NASDAQ: IRD) held a Research and Development Science Forum on June 16, 2026, where management presented updates on five gene therapy programs targeting inherited retinal diseases (IRDs).&lt;/p&gt;&lt;p&gt;The company said three programs — OPGx-RDH12, OPGx-MERTK, and OPGx-RHO — are expected to enter clinical testing within the next 12 to 18 months. OPGx-RDH12, targeting a severe form of Leber congenital amaurosis, is expected to begin U.S. clinical testing in the fourth quarter of 2026, with funding supported by the RDH12 Alliance. OPGx-MERTK, targeting autosomal recessive retinitis pigmentosa, is expected to initiate clinical testing at the Cleveland Clinic Abu Dhabi</description>
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   <pubDate>Tue, 16 Jun 2026 16:06:08 -0400</pubDate>
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   <title>Opus Genetics outlines five gene therapy programs for retinal diseases</title>
   <link>http://www.streetinsider.com/FDA/Opus+Genetics+outlines+five+gene+therapy+programs+for+retinal+diseases/26654029.html</link>
   <description>&lt;p&gt;Opus Genetics, Inc. (NASDAQ: IRD) held a Research and Development Science Forum on June 16, 2026, where management presented updates on five gene therapy programs targeting inherited retinal diseases (IRDs).&lt;/p&gt;&lt;p&gt;The company said three programs — OPGx-RDH12, OPGx-MERTK, and OPGx-RHO — are expected to enter clinical testing within the next 12 to 18 months. OPGx-RDH12, targeting a severe form of Leber congenital amaurosis, is expected to begin U.S. clinical testing in the fourth quarter of 2026, with funding supported by the RDH12 Alliance. OPGx-MERTK, targeting autosomal recessive retinitis pigmentosa, is expected to initiate clinical testing at the Cleveland Clinic Abu Dhabi</description>
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   <pubDate>Tue, 16 Jun 2026 16:06:08 -0400</pubDate>
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   <title>Opus Genetics Highlights Five Gene Therapy Programs Targeting Significant Unmet Need in Patients with Inherited Retinal Diseases</title>
   <link>http://www.streetinsider.com/Press+Releases/Opus+Genetics+Highlights+Five+Gene+Therapy+Programs+Targeting+Significant+Unmet+Need+in+Patients+with+Inherited+Retinal+Diseases/26653998.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Rapidly Advancing Five IRD Programs​&lt;/em&gt; &lt;em&gt;with Four Clinical Data Readouts Expected in 2027&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;RDH12, MERTK and RHO Programs Expected to Enter Clinical Testing over the Next 12 to 18 Months&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Cash Runway into 2029 Expected to Fund Multiple Clinical Inflection Points, Potential Product Approvals and Opportunities for Priority Review Vouchers &lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;IRD Prevalence Across Select Global Markets Provides a Significant Commercial Opportunity Across Opus Genetics’ Pipeline&lt;/em&gt;&lt;/p&gt;  &lt;p&gt;RESEARCH TRIANGLE PARK, N.C., June  16, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=YIBrzH7qmjI5zk4iViSI-jml67xKt77XtSxAckLOOw6pu0YrkfdTefmgahROcwtzoOroVJqKt-EnZXhM-3O1w_RbqiT0DWWLcInCy6NWl5E=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (the “Company” or “Opus Genetics”),</description>
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   <pubDate>Tue, 16 Jun 2026 16:05:00 -0400</pubDate>
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   <title>Opus Genetics Highlights Five Gene Therapy Programs Targeting Significant Unmet Need in Patients with Inherited Retinal Diseases</title>
   <link>http://www.streetinsider.com/Press+Releases/Opus+Genetics+Highlights+Five+Gene+Therapy+Programs+Targeting+Significant+Unmet+Need+in+Patients+with+Inherited+Retinal+Diseases/26653998.html</link>
   <description>
&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Rapidly Advancing Five IRD Programs​&lt;/em&gt; &lt;em&gt;with Four Clinical Data Readouts Expected in 2027&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;RDH12, MERTK and RHO Programs Expected to Enter Clinical Testing over the Next 12 to 18 Months&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Cash Runway into 2029 Expected to Fund Multiple Clinical Inflection Points, Potential Product Approvals and Opportunities for Priority Review Vouchers &lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;IRD Prevalence Across Select Global Markets Provides a Significant Commercial Opportunity Across Opus Genetics’ Pipeline&lt;/em&gt;&lt;/p&gt;  &lt;p&gt;RESEARCH TRIANGLE PARK, N.C., June  16, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=YIBrzH7qmjI5zk4iViSI-jml67xKt77XtSxAckLOOw6pu0YrkfdTefmgahROcwtzoOroVJqKt-EnZXhM-3O1w_RbqiT0DWWLcInCy6NWl5E=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (the “Company” or “Opus Genetics”),</description>
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   <pubDate>Tue, 16 Jun 2026 16:05:00 -0400</pubDate>
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   <title>Opus Genetics Highlights Five Gene Therapy Programs Targeting Significant Unmet Need in Patients with Inherited Retinal Diseases</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Opus+Genetics+Highlights+Five+Gene+Therapy+Programs+Targeting+Significant+Unmet+Need+in+Patients+with+Inherited+Retinal+Diseases/26653998.html</link>
   <description>
&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Rapidly Advancing Five IRD Programs​&lt;/em&gt; &lt;em&gt;with Four Clinical Data Readouts Expected in 2027&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;RDH12, MERTK and RHO Programs Expected to Enter Clinical Testing over the Next 12 to 18 Months&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Cash Runway into 2029 Expected to Fund Multiple Clinical Inflection Points, Potential Product Approvals and Opportunities for Priority Review Vouchers &lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;IRD Prevalence Across Select Global Markets Provides a Significant Commercial Opportunity Across Opus Genetics’ Pipeline&lt;/em&gt;&lt;/p&gt;  &lt;p&gt;RESEARCH TRIANGLE PARK, N.C., June  16, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=YIBrzH7qmjI5zk4iViSI-jml67xKt77XtSxAckLOOw6pu0YrkfdTefmgahROcwtzoOroVJqKt-EnZXhM-3O1w_RbqiT0DWWLcInCy6NWl5E=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (the “Company” or “Opus Genetics”),</description>
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   <pubDate>Tue, 16 Jun 2026 16:05:00 -0400</pubDate>
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   <title>Opus Genetics Highlights Five Gene Therapy Programs Targeting Significant Unmet Need in Patients with Inherited Retinal Diseases</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Opus+Genetics+Highlights+Five+Gene+Therapy+Programs+Targeting+Significant+Unmet+Need+in+Patients+with+Inherited+Retinal+Diseases/26653998.html</link>
   <description>
&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Rapidly Advancing Five IRD Programs​&lt;/em&gt; &lt;em&gt;with Four Clinical Data Readouts Expected in 2027&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;RDH12, MERTK and RHO Programs Expected to Enter Clinical Testing over the Next 12 to 18 Months&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Cash Runway into 2029 Expected to Fund Multiple Clinical Inflection Points, Potential Product Approvals and Opportunities for Priority Review Vouchers &lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;IRD Prevalence Across Select Global Markets Provides a Significant Commercial Opportunity Across Opus Genetics’ Pipeline&lt;/em&gt;&lt;/p&gt;  &lt;p&gt;RESEARCH TRIANGLE PARK, N.C., June  16, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=YIBrzH7qmjI5zk4iViSI-jml67xKt77XtSxAckLOOw6pu0YrkfdTefmgahROcwtzoOroVJqKt-EnZXhM-3O1w_RbqiT0DWWLcInCy6NWl5E=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (the “Company” or “Opus Genetics”),</description>
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   <pubDate>Tue, 16 Jun 2026 16:05:00 -0400</pubDate>
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   <title>Form  8-K        Opus Genetics, Inc.       For: Jun 16</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Opus+Genetics%2C+Inc.+++++++For%3A+Jun+16/26652749.html</link>
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   <pubDate>Tue, 16 Jun 2026 12:06:00 -0400</pubDate>
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   <title>Form  8-K        Opus Genetics, Inc.       For: Jun 16</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Opus+Genetics%2C+Inc.+++++++For%3A+Jun+16/26652749.html</link>
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   <pubDate>Tue, 16 Jun 2026 12:06:00 -0400</pubDate>
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   <title>Opus Genetics (IRD) Reiterated at Market Outperform by Citizens After Investor Meet</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Opus+Genetics+%28IRD%29+Reiterated+at+Market+Outperform+by+Citizens+After+Investor+Meet/26643352.html</link>
   <description>&lt;p&gt;Citizens analyst Jonathan Wolleben reiterated a Market Outperform rating and $11.00 price target on Opus Genetics (NASDAQ: IRD).&lt;/p&gt;&lt;p&gt;The analyst commented, &quot;We came out of our meetings with a better understanding of Opus’s big picture plans, which involve a quick, relatively inexpensive, and flexible development strategy that should be applicable across programs. As the lead candidate, OPGx-LCA5 has our highest POS at 60%, and despite a relatively modest peak sales opportunity (we model ~$150M in peak WW sales), the program will derisk the regulatory strategy and allow Opus to build out its commercial infrastructure, which will have synergistic overlap with the</description>
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   <pubDate>Mon, 15 Jun 2026 05:11:16 -0400</pubDate>
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   <title>Form  S-3        Opus Genetics, Inc.                  </title>
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   <pubDate>Fri, 05 Jun 2026 16:32:00 -0400</pubDate>
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   <title>Form  S-3        Opus Genetics, Inc.                  </title>
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   <pubDate>Fri, 05 Jun 2026 16:32:00 -0400</pubDate>
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   <title>Guggenheim Starts Opus Genetics (IRD) at Buy</title>
   <link>http://www.streetinsider.com/New+Coverage/Guggenheim+Starts+Opus+Genetics+%28IRD%29+at+Buy/26601983.html</link>
   <description>&lt;p&gt;Guggenheim analyst Debjit Chattopadhyay initiates coverage on Opus Genetics (NASDAQ: IRD) with a Buy rating and a price target of $16.00.&lt;/p&gt;&lt;p&gt;For an analyst ratings summary and ratings history on Opus Genetics &lt;a href=&quot;http://www.streetinsider.com/rating_history.php?q=IRD&quot;&gt;click here&lt;/a&gt;. For more ratings news on Opus Genetics &lt;a href=&quot;http://www.streetinsider.com/stock_lookup_news.php?q=IRD&amp;amp;type=analyst&quot;&gt;click here&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;Shares of Opus Genetics closed at $4.20 yesterday.&lt;/p&gt;</description>
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   <pubDate>Thu, 04 Jun 2026 06:10:07 -0400</pubDate>
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   <title>Opus Genetics to Host Virtual R&amp;amp;D Science Forum on Tuesday, June 16, 2026 Featuring Multiple Inherited Retinal Disease Experts</title>
   <link>http://www.streetinsider.com/Press+Releases/Opus+Genetics+to+Host+Virtual+R%26amp%3BD+Science+Forum+on+Tuesday%2C+June+16%2C+2026+Featuring+Multiple+Inherited+Retinal+Disease+Experts/26587193.html</link>
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&lt;p align=&quot;left&quot;&gt;RESEARCH TRIANGLE PARK, N.C., June  02, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=vwcpbrik_gRnvGXv10KcmaZtEEG4TdQ3-EmqJI42LZGBbWFpwHbWVuXiDsM4IjgwZHmlmzsXT2hxWwGEHUCvLdm3R0y3Ja_Ai9aYA2C0rkA=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (“Opus Genetics” or the “Company”), a clinical-stage biopharmaceutical company developing gene therapies to restore vision and prevent blindness in patients with inherited retinal diseases (IRDs), today announced the guest speakers for its virtual Research &amp;amp; Development (R&amp;amp;D) Science Forum to be held on Tuesday, June 16, 2026, from 10:00 am – 12:00 pm ET.&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;The R&amp;amp;D Science Forum will feature management and key opinion leaders (KOLs) highlighting Opus Genetics’ multi-asset gene therapy pipeline, which is designed</description>
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   <title>Opus Genetics to Host Virtual R&amp;amp;D Science Forum on Tuesday, June 16, 2026 Featuring Multiple Inherited Retinal Disease Experts</title>
   <link>http://www.streetinsider.com/Press+Releases/Opus+Genetics+to+Host+Virtual+R%26amp%3BD+Science+Forum+on+Tuesday%2C+June+16%2C+2026+Featuring+Multiple+Inherited+Retinal+Disease+Experts/26587193.html</link>
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&lt;p align=&quot;left&quot;&gt;RESEARCH TRIANGLE PARK, N.C., June  02, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=vwcpbrik_gRnvGXv10KcmaZtEEG4TdQ3-EmqJI42LZGBbWFpwHbWVuXiDsM4IjgwZHmlmzsXT2hxWwGEHUCvLdm3R0y3Ja_Ai9aYA2C0rkA=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (“Opus Genetics” or the “Company”), a clinical-stage biopharmaceutical company developing gene therapies to restore vision and prevent blindness in patients with inherited retinal diseases (IRDs), today announced the guest speakers for its virtual Research &amp;amp; Development (R&amp;amp;D) Science Forum to be held on Tuesday, June 16, 2026, from 10:00 am – 12:00 pm ET.&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;The R&amp;amp;D Science Forum will feature management and key opinion leaders (KOLs) highlighting Opus Genetics’ multi-asset gene therapy pipeline, which is designed</description>
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   <title>Opus Genetics to Host Virtual R&amp;amp;D Science Forum on Tuesday, June 16, 2026 Featuring Multiple Inherited Retinal Disease Experts</title>
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   <title>Opus Genetics to Host Virtual R&amp;amp;D Science Forum on Tuesday, June 16, 2026 Featuring Multiple Inherited Retinal Disease Experts</title>
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&lt;p align=&quot;left&quot;&gt;RESEARCH TRIANGLE PARK, N.C., June  02, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=vwcpbrik_gRnvGXv10KcmaZtEEG4TdQ3-EmqJI42LZGBbWFpwHbWVuXiDsM4IjgwZHmlmzsXT2hxWwGEHUCvLdm3R0y3Ja_Ai9aYA2C0rkA=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (“Opus Genetics” or the “Company”), a clinical-stage biopharmaceutical company developing gene therapies to restore vision and prevent blindness in patients with inherited retinal diseases (IRDs), today announced the guest speakers for its virtual Research &amp;amp; Development (R&amp;amp;D) Science Forum to be held on Tuesday, June 16, 2026, from 10:00 am – 12:00 pm ET.&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;The R&amp;amp;D Science Forum will feature management and key opinion leaders (KOLs) highlighting Opus Genetics’ multi-asset gene therapy pipeline, which is designed</description>
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&lt;p align=&quot;left&quot;&gt;RESEARCH TRIANGLE PARK, N.C., June  02, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=vwcpbrik_gRnvGXv10KcmaZtEEG4TdQ3-EmqJI42LZGBbWFpwHbWVuXiDsM4IjgwZHmlmzsXT2hxWwGEHUCvLdm3R0y3Ja_Ai9aYA2C0rkA=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Opus Genetics, Inc.&lt;/a&gt; (Nasdaq: IRD) (“Opus Genetics” or the “Company”), a clinical-stage biopharmaceutical company developing gene therapies to restore vision and prevent blindness in patients with inherited retinal diseases (IRDs), today announced the guest speakers for its virtual Research &amp;amp; Development (R&amp;amp;D) Science Forum to be held on Tuesday, June 16, 2026, from 10:00 am – 12:00 pm ET.&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;The R&amp;amp;D Science Forum will feature management and key opinion leaders (KOLs) highlighting Opus Genetics’ multi-asset gene therapy pipeline, which is designed</description>
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