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   <title>Form  6-K        GH Research PLC           For: Jun 04</title>
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   <title>Form  6-K        GH Research PLC           For: Jun 04</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++6-K++++++++GH+Research+PLC+++++++++++For%3A+Jun+04/26603046.html</link>
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   <title>GH Research publishes Phase 2a postpartum depression trial results</title>
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&lt;p&gt;GH Research PLC (NASDAQ: GHRS) announced the publication of results from its Phase 2a trial of inhaled mebufotenin (GH001) for postpartum depression in The Journal of Clinical Psychiatry.&lt;/p&gt;

&lt;p&gt;The single-arm, open-label trial enrolled 10 adult women with postpartum depression. The study met its primary endpoint with a mean Montgomery–Åsberg Depression Rating Scale reduction of 35.4 points from baseline to Day 8. All 10 patients achieved remission within two hours of dosing, which was sustained through Day 8.&lt;/p&gt;

&lt;p&gt;The trial showed a 34.1-point increase on the Barkin Index of Maternal Functioning at Day 8, representing a 56% improvement. The treatment was well-tolerated with</description>
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   <pubDate>Thu, 04 Jun 2026 07:01:08 -0400</pubDate>
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   <title>GH Research publishes Phase 2a postpartum depression trial results</title>
   <link>http://www.streetinsider.com/FDA/GH+Research+publishes+Phase+2a+postpartum+depression+trial+results/26602338.html</link>
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&lt;p&gt;GH Research PLC (NASDAQ: GHRS) announced the publication of results from its Phase 2a trial of inhaled mebufotenin (GH001) for postpartum depression in The Journal of Clinical Psychiatry.&lt;/p&gt;

&lt;p&gt;The single-arm, open-label trial enrolled 10 adult women with postpartum depression. The study met its primary endpoint with a mean Montgomery–Åsberg Depression Rating Scale reduction of 35.4 points from baseline to Day 8. All 10 patients achieved remission within two hours of dosing, which was sustained through Day 8.&lt;/p&gt;

&lt;p&gt;The trial showed a 34.1-point increase on the Barkin Index of Maternal Functioning at Day 8, representing a 56% improvement. The treatment was well-tolerated with</description>
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   <title>GH Research publishes Phase 2a postpartum depression trial results</title>
   <link>http://www.streetinsider.com/FDA/GH+Research+publishes+Phase+2a+postpartum+depression+trial+results/26602338.html</link>
   <description>

&lt;p&gt;GH Research PLC (NASDAQ: GHRS) announced the publication of results from its Phase 2a trial of inhaled mebufotenin (GH001) for postpartum depression in The Journal of Clinical Psychiatry.&lt;/p&gt;

&lt;p&gt;The single-arm, open-label trial enrolled 10 adult women with postpartum depression. The study met its primary endpoint with a mean Montgomery–Åsberg Depression Rating Scale reduction of 35.4 points from baseline to Day 8. All 10 patients achieved remission within two hours of dosing, which was sustained through Day 8.&lt;/p&gt;

&lt;p&gt;The trial showed a 34.1-point increase on the Barkin Index of Maternal Functioning at Day 8, representing a 56% improvement. The treatment was well-tolerated with</description>
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   <title>GH Research publishes Phase 2a postpartum depression trial results</title>
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   <description>

&lt;p&gt;GH Research PLC (NASDAQ: GHRS) announced the publication of results from its Phase 2a trial of inhaled mebufotenin (GH001) for postpartum depression in The Journal of Clinical Psychiatry.&lt;/p&gt;

&lt;p&gt;The single-arm, open-label trial enrolled 10 adult women with postpartum depression. The study met its primary endpoint with a mean Montgomery–Åsberg Depression Rating Scale reduction of 35.4 points from baseline to Day 8. All 10 patients achieved remission within two hours of dosing, which was sustained through Day 8.&lt;/p&gt;

&lt;p&gt;The trial showed a 34.1-point increase on the Barkin Index of Maternal Functioning at Day 8, representing a 56% improvement. The treatment was well-tolerated with</description>
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   <title>GH Research publishes Phase 2a postpartum depression trial results</title>
   <link>http://www.streetinsider.com/FDA/GH+Research+publishes+Phase+2a+postpartum+depression+trial+results/26602338.html</link>
   <description>

&lt;p&gt;GH Research PLC (NASDAQ: GHRS) announced the publication of results from its Phase 2a trial of inhaled mebufotenin (GH001) for postpartum depression in The Journal of Clinical Psychiatry.&lt;/p&gt;

&lt;p&gt;The single-arm, open-label trial enrolled 10 adult women with postpartum depression. The study met its primary endpoint with a mean Montgomery–Åsberg Depression Rating Scale reduction of 35.4 points from baseline to Day 8. All 10 patients achieved remission within two hours of dosing, which was sustained through Day 8.&lt;/p&gt;

&lt;p&gt;The trial showed a 34.1-point increase on the Barkin Index of Maternal Functioning at Day 8, representing a 56% improvement. The treatment was well-tolerated with</description>
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   <title>GH Research publishes Phase 2a postpartum depression trial results</title>
   <link>http://www.streetinsider.com/FDA/GH+Research+publishes+Phase+2a+postpartum+depression+trial+results/26602338.html</link>
   <description>

&lt;p&gt;GH Research PLC (NASDAQ: GHRS) announced the publication of results from its Phase 2a trial of inhaled mebufotenin (GH001) for postpartum depression in The Journal of Clinical Psychiatry.&lt;/p&gt;

&lt;p&gt;The single-arm, open-label trial enrolled 10 adult women with postpartum depression. The study met its primary endpoint with a mean Montgomery–Åsberg Depression Rating Scale reduction of 35.4 points from baseline to Day 8. All 10 patients achieved remission within two hours of dosing, which was sustained through Day 8.&lt;/p&gt;

&lt;p&gt;The trial showed a 34.1-point increase on the Barkin Index of Maternal Functioning at Day 8, representing a 56% improvement. The treatment was well-tolerated with</description>
   <guid isPermaLink="true">http://www.streetinsider.com/FDA/GH+Research+publishes+Phase+2a+postpartum+depression+trial+results/26602338.html</guid>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
   <link>http://www.streetinsider.com/Press+Releases/GH+Research+Announces+Publication+of+Phase+2a+Postpartum+Depression+Results/26602325.html</link>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/GH+Research+Announces+Publication+of+Phase+2a+Postpartum+Depression+Results/26602325.html</guid>
   <pubDate>Thu, 04 Jun 2026 07:00:00 -0400</pubDate>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/GH+Research+Announces+Publication+of+Phase+2a+Postpartum+Depression+Results/26602325.html</guid>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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   <title>GH Research Announces Publication of Phase 2a Postpartum Depression Results</title>
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&lt;p align=&quot;justify&quot;&gt;DUBLIN, June  04, 2026  (GLOBE NEWSWIRE) -- GH Research PLC (Nasdaq: GHRS) today announced the publication of the full results from its Phase 2a trial in postpartum depression (PPD) and the acceptance of two oral presentations at the 37th World Congress of Neuropsychopharmacology (CINP 2026).&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The peer-reviewed article, titled “Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression: A Phase 2a Open-Label Clinical Trial,” has been published in &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=5rbDghxikGo6xioAi_0w2azVzgLQk8gXxvBs7W94uwK79Jq98SpaxQNPoW9vPXpH2v2Nz0ivHGUI-v7X4aNDZQxPUHviZJzX8fYndbR734xYZv2yWHib4A9T-Le1uiqgfsJ3mqH4ScVp_XR-W2Owtw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;The Journal of Clinical Psychiatry&lt;/a&gt; (DOI: 10.4088/JCP.25m16284). The article reports the full results from the Phase 2a, single-arm, open-label trial, which enrolled 10</description>
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   <pubDate>Wed, 20 May 2026 06:04:00 -0400</pubDate>
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   <description>(Updated - May 19, 2026 6:51 AM EDT)

&lt;p&gt;H.C. Wainwright analyst Patrick R. Trucchio lowered the price target on GH Research PLC (NASDAQ: GHRS) to $65.00 (from $70.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;On May 14, GH Research reported 1Q26 results and a series of incremental updates that further de-risk the path toward initiation of the global Phase 3 trial evaluating GH001 in treatment-resistant depression (TRD) expected late 2026. Key developments include: (1) publication of the Phase 2b trial (GH001-TRD-201) results in JAMA Psychiatry, including a post-hoc analysis showing Day 8 remission rates of 53.9% to 63.6% across subgroups</description>
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