Neurosense Therapeutics (NRSN) CEO Issues Q3 2023 Update

NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) ("NeuroSense"), a company developing treatments for severe neurodegenerative diseases, today provided an update from its CEO, Alon Ben-Noon, on the Company's clinical and operational developments during and immediately following the third quarter of 2023. The Company's amyotrophic lateral sclerosis (ALS) Phase 2b PARADIGM trial of PrimeC is expected to report clinical topline results Q4 2023, and a Phase 2 Alzheimer's disease study is expected to enroll the first patient in the next several weeks.

Non-Sponsored Study Demonstrated PrimeC has Outstanding Effect on ALS Survival (LINK)

• At the Ichida Stem Cell Lab at University of Southern California, PrimeC was shown to significantly increase survival rate of induced motor neurons in an in vitro study utilizing induced pluripotent stem cells (iPSCs) generated from people living with ALS
• In another independent study carried out by Dr. Ichida in an Innovative iPSC model, PrimeC performed among the best in improving motor neuron survival when compared to several other ALS drugs in development and two ALS FDA approved drugs

Received SME Status from European Medicines Agency & Opened Office in Germany (LINK)

• Small and Medium-Sized Enterprise (SME) status offers regulatory guidance and engagement in dialogue with EMA
• Company plans to enroll patients at multiple sites across Europe in its planned Phase 3 pivotal ALS study of PrimeC

Granted Patents in Europe, Japan, and Israel for PrimeC (LINK)

• Patents valid through 2038

Ended At-The-Market Equity Offering Program (LINK)

• Company is fully funded into Q2 2024 beyond clinical Phase 2b ALS results expected Q4 2023

"On October 7, Israel endured an unprecedented brutal attack, a massacre, by heinous terrorists identifying themselves as Hamas. I'm relieved to report that everyone at NeuroSense is safe. However, we are heartbroken by this dreadful event and the number of brutally murdered and abducted innocent civilians. In the face of such terror, NeuroSense's response remains resolute: we will continue to advance the frontiers of science and invest every effort into developing effective neurological treatments for those in desperate need, without hesitation. Resilience and unity are key here, and therefore we are also assisting people in dire need to recover and rebuild," stated Alon Ben-Noon, CEO of NeuroSense. "NeuroSense had a very strong third quarter, as we confidently look ahead to reporting Phase 2b ALS clinical results for PrimeC before the end of the year. The outstanding results from a non-sponsored study of PrimeC in an innovative ALS model further validate the results we've been seeing in our human clinicals and in biomarker and in vitro studies."

You May Also Be Interested In

• Teva submits NDA for ecopipam to treat pediatric Tourette syndrome
• Hamilton Beach Brands senior VP and general counsel departs
• ScottsMiracle-Gro names Nick Miaritis as chief brand officer