Axsome Therapeutics (AXSM) PT Raised to $380 at Jefferies

June 11, 2026 5:34 AM EDT
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Price: $233.80 -6.09%

Rating Summary:
    25 Buy, 1 Hold, 0 Sell

Rating Trend: Up Up

Today's Overall Ratings:
    Up: 14 | Down: 11 | New: 17
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Jefferies analyst Andrew Tsai raised the price target on Axsome Therapeutics (NASDAQ: AXSM) to $380.00 (from $275.00) while maintaining a Buy rating.

The analyst comments "Based on our (+) KOL discussions, we believe Auvelity's combined peak sales in major depression (MDD) and Alzheimer's agitation (AADAD) could surpass $6B+ (or $3B apiece), up from a $610M+ runrate in MDD-only - still conservative vs mgmt's $8B guidance. Ultimately, $6B of sales x 3x multiple (long IP tail) = $18B+ valuation (vs $12.5B cap), making AXSM's late-stage CNS pipeline (10+ indications) mostly call options - raising PT to $380."



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